Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447450 | 0.95 | PRSS1 (0.42) | PRSS1PRSS2PRSS3PARP1CYP3A4 | |
| SCHEMBL1172633 | 0.87 | TSHR (0.39) | PRSS1PRSS2PRSS3PARP1CYP3A4 | |
| SCHEMBL5898518 | 0.87 | PARP10 (0.49) | PRSS1PRSS2PRSS3PARP1CYP3A4 | |
| SCHEMBL16951666 | 0.85 | CYP4F2 (0.47) | PRSS1PRSS2PRSS3PARP1CYP3A4 | |
| SCHEMBL3488223 | 0.85 | ADRA1D (0.50) | PRSS1PRSS2PRSS3PARP1CYP3A4 | |
| SCHEMBL14434766 | 0.82 | PRSS1 (0.34) | PRSS1PRSS2PRSS3PARP1CYP3A4 | |
| SCHEMBL2791068 | 0.80 | PRKCA (0.49) | PRKCAPRKCDDHODH | |
| SCHEMBL31469843 | 0.80 | PLAU (0.42) | PARP1CYP3A4SMN1; SMN2TSHRPLA2G10 | |
| SCHEMBL1172020 | 0.79 | CYP3A4 (0.70) | PRSS1PRSS2PRSS3PARP1CYP3A4 | |
| SCHEMBL1004651 | 0.78 | RXRA (0.47) | PARP1CYP3A4SMN1; SMN2TSHRPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |