Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22416125 | 0.90 | MAOB (0.77) | MAOBNPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL398187 | 0.89 | MAOB (0.75) | MAOBNPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL4510662 | 0.80 | LMNA (0.65) | MAOBNPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL10341234 | 0.79 | KDM4E (0.72) | MAOBNPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL6005094 | 0.79 | MAOB (0.61) | MAOBNPC1LMNAKMT2AMAPT | |
| SCHEMBL28689795 | 0.79 | MAPT (0.62) | MAOBNPC1RAB9ALMNAMEN1 | |
| SCHEMBL28689792 | 0.79 | MAPT (0.62) | MAOBNPC1RAB9ALMNAMEN1 | |
| SCHEMBL30263098 | 0.79 | MAPT (0.62) | MAOBNPC1RAB9ALMNAMEN1 | |
| SCHEMBL24254462 | 0.78 | LMNA (0.71) | MAOBNPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL30542058 | 0.78 | LMNA (0.71) | MAOBNPC1RAB9AS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056724-B1 | SUBSTITUTED CYCLOALKYL-4-OXONICOTINIC CARBOXAMIDES; GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-05-25 | — | — | EP | disclosed |