Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | CTSK | P43235 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 10/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163361 | 1.00 | CTSL (0.60) | CTSLCTSSCTSKKMT2AMC4R | |
| SCHEMBL6160248 | 0.92 | CTSL (0.51) | CTSLCTSSCTSKKMT2AMC4R | |
| SCHEMBL6161491 | 0.88 | CALCRL (0.49) | CTSLCTSSCTSKCALCRLCYP3A4 | |
| SCHEMBL6161500 | 0.88 | CALCRL (0.49) | CTSLCTSSCTSKCALCRLCYP3A4 | |
| Hydrochloric Acid SCHEMBL6161553 | 0.87 | CALCRL (0.49) | CTSLCTSSCTSKCALCRLCYP3A4 | |
| Hydrochloric Acid SCHEMBL6161544 | 0.87 | CALCRL (0.49) | CTSLCTSSCTSKCALCRLCYP3A4 | |
| SCHEMBL2374758 | 0.83 | KMT2A (0.68) | CTSLCTSSCTSKKMT2AMAPK1 | |
| SCHEMBL2374766 | 0.83 | KMT2A (0.68) | CTSLCTSSCTSKKMT2AMAPK1 | |
| SCHEMBL5552595 | 0.83 | CTSS (0.63) | CTSLCTSSCTSKKMT2AMC4R | |
| SCHEMBL8409751 | 0.81 | KMT2A (0.56) | CTSSCTSKKMT2AMAPK1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |