Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2374766 | 0.89 | KMT2A (0.68) | KMT2ACTSSCTSKMAPK1PABPC1 | |
| SCHEMBL2374758 | 0.89 | KMT2A (0.68) | KMT2ACTSSCTSKMAPK1PABPC1 | |
| SCHEMBL6163361 | 0.81 | CTSL (0.60) | KMT2ACTSSCTSKMAPK1PABPC1 | |
| SCHEMBL6163357 | 0.81 | CTSL (0.60) | KMT2ACTSSCTSKMAPK1PABPC1 | |
| SCHEMBL29682591 | 0.80 | KMT2A (0.56) | KMT2ACTSSCTSKMAPK1PABPC1 | |
| SCHEMBL6161108 | 0.80 | PPARG (0.59) | KMT2AMAPK1PABPC1HRH2HRH1 | |
| SCHEMBL6161114 | 0.80 | PPARG (0.59) | KMT2AMAPK1PABPC1HRH2HRH1 | |
| SCHEMBL6162815 | 0.79 | KMT2A (0.71) | KMT2ACTSSCTSKMAPK1PABPC1 | |
| SCHEMBL6162477 | 0.79 | KMT2A (0.71) | KMT2ACTSSCTSKMAPK1PABPC1 | |
| SCHEMBL6162484 | 0.79 | KMT2A (0.71) | KMT2ACTSSCTSKMAPK1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |