Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688284 | 0.80 | POLB (0.38) | POLB | |
| SCHEMBL77388 | 0.80 | POLB (0.33) | POLB | |
| SCHEMBL9697351 | 0.78 | POLB (0.32) | POLB | |
| SCHEMBL2714868 | 0.77 | KMT2A (0.32) | KMT2A | |
| SCHEMBL13803836 | 0.76 | BDKRB2 (0.41) | BDKRB2POLBKMT2A | |
| SCHEMBL6167979 | 0.75 | MEN1 (0.36) | KMT2ALMNA | |
| SCHEMBL14979751 | 0.72 | PLA2G7 (0.30) | — | |
| SCHEMBL13269817 | 0.71 | — | — | |
| SCHEMBL9469145 | 0.71 | KMT2A (0.32) | KMT2A | |
| SCHEMBL9651668 | 0.70 | KMT2A (0.32) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133490-B1 | PIPERAZINONE DERIVATIVES | CIBA SC HOLDING AG (CH) | 2005-07-27 | — | — | EP | disclosed |
| US-6596461-B1 | Useful for stabilizing an organic material against degradation induced by light, heat or oxidation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |
| EP-1133490-A1 | PIPERAZINONE DERIVATIVES | Ciba SC Holding AG (CH) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000031069-A1 | PIPERAZINONE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-06-02 | — | — | WO | disclosed |