Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688284 | 0.78 | POLB (0.38) | — | |
| SCHEMBL77388 | 0.78 | POLB (0.33) | — | |
| SCHEMBL9697351 | 0.77 | POLB (0.32) | — | |
| SCHEMBL2714868 | 0.76 | KMT2A (0.32) | KMT2A | |
| SCHEMBL6163515 | 0.75 | BDKRB2 (0.36) | KMT2ALMNA | |
| SCHEMBL7195890 | 0.74 | — | — | |
| SCHEMBL9119329 | 0.74 | PLA2G7 (0.31) | MEN1KMT2A | |
| SCHEMBL6938640 | 0.73 | PIK3CD (0.33) | MEN1KMT2ATSHRPIK3CDHSD17B10 | |
| SCHEMBL9326406 | 0.73 | OPRM1 (0.32) | — | |
| SCHEMBL10486753 | 0.73 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642383-B2 | Of the class 3,3,5,5-tetramethyl-2-oxo-1,4-piperazine, polymers thereof; stabilizers for thermoplastic organic polymers, coating compositions or photographic materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-11-04 | — | — | US | claimed |
| US-20020115859-A1 | Oxopiperazinyl derivatives and light stabilized compositions | LAZZARI DARIO (IT) | 2002-08-22 | — | — | US | claimed |
| EP-1133490-B1 | PIPERAZINONE DERIVATIVES | CIBA SC HOLDING AG (CH) | 2005-07-27 | — | — | EP | disclosed |
| US-6642383-B2 | Of the class 3,3,5,5-tetramethyl-2-oxo-1,4-piperazine, polymers thereof; stabilizers for thermoplastic organic polymers, coating compositions or photographic materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-11-04 | — | — | US | disclosed |
| US-6596461-B1 | Useful for stabilizing an organic material against degradation induced by light, heat or oxidation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |
| US-20020115859-A1 | Oxopiperazinyl derivatives and light stabilized compositions | LAZZARI DARIO (IT) | 2002-08-22 | — | — | US | disclosed |
| EP-1133490-A1 | PIPERAZINONE DERIVATIVES | Ciba SC Holding AG (CH) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000031069-A1 | PIPERAZINONE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115859-A1 | Oxopiperazinyl derivatives and light stabilized compositions | CBR1, PYM1, CCT4 | MEN1 3739/4885KMT2A 654/4885TSHR 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.