Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | YAP1 | P46937 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161717 | 0.92 | MAPK1 (0.50) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL6161724 | 0.92 | MAPK1 (0.50) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL6162910 | 0.91 | MAPK1 (0.48) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL8410099 | 0.88 | MC4R (0.43) | — | |
| SCHEMBL6166213 | 0.88 | MAPK1 (0.49) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL6166209 | 0.88 | MAPK1 (0.49) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| Hydrochloric Acid SCHEMBL6162871 | 0.86 | MC4R (0.46) | CAPN1CTSBCTSSCTSKCCR1 | |
| Hydrochloric Acid SCHEMBL6162865 | 0.86 | MC4R (0.46) | CAPN1CTSBCTSSCTSKCCR1 | |
| SCHEMBL6168383 | 0.85 | MAPK1 (0.51) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL6168374 | 0.85 | MAPK1 (0.51) | MAPK1KMT2ACAPN1CTSBYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |