Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | YAP1 | P46937 | 3/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166209 | 1.00 | MAPK1 (0.49) | MAPK1KMT2ANR1H2CAPN1CTSB | |
| SCHEMBL6161724 | 0.90 | MAPK1 (0.50) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL6161717 | 0.90 | MAPK1 (0.50) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL6168383 | 0.88 | MAPK1 (0.51) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL6168374 | 0.88 | MAPK1 (0.51) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL6163821 | 0.88 | MAPK1 (0.48) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL8412367 | 0.87 | TACR1 (0.45) | NR1H2 | |
| SCHEMBL6162910 | 0.87 | MAPK1 (0.48) | MAPK1KMT2ACAPN1CTSBYAP1 | |
| SCHEMBL6161443 | 0.84 | P2RX7 (0.47) | MAPK1KMT2ASTSALDH1A1F10 | |
| SCHEMBL6162909 | 0.83 | MAPK1 (0.62) | MAPK1KMT2ACAPN1CTSBYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |