Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.89 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163899 | 1.00 | ACHE (0.89) | ACHETRPV1FGFR1 | |
| SCHEMBL8232286 | 0.83 | ACHE (0.61) | ACHEFGFR1 | |
| SCHEMBL7724052 | 0.83 | ACHE (0.61) | ACHEFGFR1 | |
| SCHEMBL2123701 | 0.82 | TRPV1 (0.87) | ACHETRPV1 | |
| SCHEMBL2123698 | 0.82 | TRPV1 (0.87) | ACHETRPV1 | |
| SCHEMBL5029885 | 0.82 | TRPV1 (0.87) | ACHETRPV1 | |
| SCHEMBL31533012 | 0.78 | GPR183 (0.73) | ACHETRPV1 | |
| SCHEMBL2122818 | 0.78 | L3MBTL1 (0.81) | ACHETRPV1 | |
| SCHEMBL2122822 | 0.78 | L3MBTL1 (0.81) | ACHETRPV1 | |
| SCHEMBL17327997 | 0.78 | TRPV1 (0.97) | ACHETRPV1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |