Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232286 | 1.00 | ACHE (0.61) | ACHEFGFR1GAAKMT2AALDH1A1 | |
| SCHEMBL6163904 | 0.83 | ACHE (0.89) | ACHEFGFR1 | |
| SCHEMBL6163899 | 0.83 | ACHE (0.89) | ACHEFGFR1 | |
| SCHEMBL6160266 | 0.82 | LTA4H (0.55) | GAAKMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL6160259 | 0.82 | LTA4H (0.55) | GAAKMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL6160900 | 0.81 | ACHE (0.48) | ACHEGAAKMT2AALDH1A1MAPT | |
| SCHEMBL3364855 | 0.78 | APP (0.62) | FGFR1GAAKMT2AALDH1A1ABCB1 | |
| SCHEMBL3364853 | 0.78 | APP (0.62) | FGFR1GAAKMT2AALDH1A1ABCB1 | |
| SCHEMBL11585649 | 0.71 | MAPT (0.53) | ACHEGAAKMT2AALDH1A1ABCB1 | |
| SCHEMBL11585652 | 0.71 | MAPT (0.53) | ACHEGAAKMT2AALDH1A1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |