Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 19/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157630 | 0.83 | CASP1 (1.00) | CASP1 | |
| SCHEMBL6157629 | 0.83 | CASP1 (1.00) | CASP1 | |
| SCHEMBL6157640 | 0.83 | CASP1 (1.00) | CASP1 | |
| SCHEMBL6160430 | 0.74 | CASP1 (0.77) | CASP1 | |
| SCHEMBL6160428 | 0.74 | CASP1 (0.77) | CASP1 | |
| SCHEMBL6158900 | 0.70 | CASP1 (0.38) | CASP1 | |
| SCHEMBL6159342 | 0.68 | CASP1 (0.60) | CASP1 | |
| SCHEMBL6159306 | 0.67 | CASP1 (0.71) | CASP1 | |
| SCHEMBL6159731 | 0.67 | CASP1 (0.71) | CASP1 | |
| SCHEMBL5329567 | 0.66 | KMT2A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |