Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167189 | 0.84 | DHODH (0.31) | DHODH | |
| SCHEMBL6166965 | 0.84 | ABCG2 (0.36) | — | |
| SCHEMBL6166859 | 0.83 | HTT (0.39) | — | |
| SCHEMBL6164973 | 0.79 | DHODH (0.36) | DHODH | |
| SCHEMBL6162163 | 0.78 | DHODH (0.41) | DHODH | |
| SCHEMBL6166482 | 0.78 | DHODH (0.36) | DHODH | |
| SCHEMBL6770489 | 0.76 | DHODH (0.35) | DHODH | |
| SCHEMBL6168301 | 0.75 | SMN1; SMN2 (0.43) | DHODH | |
| SCHEMBL6167293 | 0.75 | HTT (0.42) | — | |
| SCHEMBL6772419 | 0.74 | SRC (0.39) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177185-B1 | 4, 5, 6, 7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-04-20 | — | — | EP | disclosed |
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |