Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412738 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAMMP2MMP9 | |
| SCHEMBL6161694 | 0.90 | MEN1 (0.45) | MAPTMEN1KMT2ATACR1CTSL | |
| SCHEMBL6161487 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MAPTGAAMMP2MMP9 | |
| SCHEMBL6161482 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MAPTGAAMMP2MMP9 | |
| Hydrochloric Acid SCHEMBL6161150 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAMMP2MMP9 | |
| Hydrochloric Acid SCHEMBL6161152 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAMMP2MMP9 | |
| SCHEMBL6160909 | 0.85 | CTSL (0.50) | MAPTMEN1KMT2ATACR1CTSL | |
| SCHEMBL6163734 | 0.85 | TACR1 (0.48) | MAPTMEN1KMT2ATACR1CTSL | |
| SCHEMBL6163736 | 0.85 | TACR1 (0.48) | MAPTMEN1KMT2ATACR1CTSL | |
| SCHEMBL6169899 | 0.85 | MMP2 (0.45) | MAPTMMP2MMP9MMP8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |