SCHEMBL6165559

SCHEMBL6165559

C=C(OCC)c1cc(NC(C)=O)c(Cl)c(C(=O)OC)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 6/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 2/20 0.39
GALR2 O43603 1/20 0.39
MITF O75030 1/20 0.39
POLB P06746 1/20 0.39
HSP90AA1 P07900 1/20 0.39
XBP1 P17861 1/20 0.39
CCR6 P51684 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KMT2A Q03164 1/20 0.38
GPR35 Q9HC97 1/20 0.38
RORC P51449 1/20 0.37
GABRA2 P47869 1/20 0.37
GABRB2 P47870 1/20 0.37
KDM4E B2RXH2 2/20 0.36
IAPP P10997 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20955429 0.85 ALDH1A1 (0.43) ALDH1A1LMNANPSR1KDM4EIAPP
SCHEMBL14356406 0.84 GLP1R (0.40) SMN1; SMN2ALDH1A1POLBXBP1NPSR1
SCHEMBL16776856 0.83 ALDH1A1 (0.42) ALDH1A1LMNANPSR1KMT2AGPR35
SCHEMBL13843758 0.81 NQO2 (0.41) SMN1; SMN2ALDH1A1LMNAPOLBXBP1
SCHEMBL6166698 0.79 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1LMNANPSR1GPR35
SCHEMBL20727067 0.78 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1POLBNPSR1KMT2A
SCHEMBL13843652 0.77 NQO2 (0.41) SMN1; SMN2ALDH1A1HPGDXBP1NPSR1
SCHEMBL2338797 0.76 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1LMNANPSR1KDM4E
SCHEMBL32669001 0.76 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1LMNANPSR1KDM4E
SCHEMBL16029610 0.74 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1LMNANPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1414814-B1 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2005-02-02 EP disclosed
US-6784137-B2 SUCH AS 5,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID-N-OXIDE FOR PREEMERGENCE APPLICATION DOW AGROSCIENCES LLC 2004-08-31 US disclosed
US-20030114311-A1 6-Aryl-4-aminopicolinates and their use as herbicides CORTEVA AGRISCIENCE LLC 2003-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114311-A1 6-Aryl-4-aminopicolinates and their use as herbicides AADAC, DDT, AADAT SMN1; SMN2 4252/4885ALDH1A1 713/4885LMNA 4347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.