SCHEMBL6165853

SCHEMBL6165853

CCC(C)(C)OOCC(C)c1ccccc1C(C)COOC(C)(C)CC

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
RIPK1 Q13546 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48451 0.83 TSHR (0.35) TSHRRIPK1
SCHEMBL6166517 0.81 RIPK1 (0.32) TSHRRIPK1
SCHEMBL7937714 0.79 HDAC4 (0.35) RIPK1
SCHEMBL21268000 0.75 TSHR (0.33) TSHRRIPK1
SCHEMBL16703326 0.73
SCHEMBL20302226 0.73 GBA1 (0.35)
SCHEMBL10811127 0.71 MAPK1 (0.33) TSHR
SCHEMBL16703274 0.70
SCHEMBL18301597 0.70 ALDH1A1 (0.36) TSHR
SCHEMBL10541555 0.69 TSHR (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239968-A1 Process for preparing graft polyols using enol ethers as reaction moderators BASF CORPORATION 2005-10-27 US disclosed
EP-1589051-A1 Process for preparing graft polyols using enol ethers as reaction moderators BASF Corporation (US) 2005-10-26 EP disclosed
EP-1192198-A1 PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR BASF CORPORATION (US) 2002-04-03 EP disclosed
US-6172164-B1 POLYMERIZING AN ETHYLENICALLY UNSATURATED MONOMER WITH A MACROMER WITH UNSATURATION IN PRESENCE OF FREE RADICAL INITIATOR BLEND OF TERT-AMYL PEROXY (2-ETHYLHEXANOATE AND 1,1'BIS(TERT-AMYL PEROXY) CYCLOHEXANE BASF CORPORATION 2001-01-09 US disclosed
WO-2000059971-A1 PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR BASF CORPORATION (DE) 2000-10-12 WO disclosed