Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16703326 | 0.86 | — | — | |
| SCHEMBL7937714 | 0.86 | HDAC4 (0.35) | RIPK1 | |
| SCHEMBL361156 | 0.82 | RIPK1 (0.35) | RIPK1ALDH1A1TSHRGRIA4 | |
| SCHEMBL6165853 | 0.81 | TSHR (0.36) | RIPK1TSHR | |
| SCHEMBL16703274 | 0.80 | — | — | |
| SCHEMBL4084906 | 0.77 | IDO1 (0.37) | RIPK1GRIA4 | |
| SCHEMBL20302226 | 0.75 | GBA1 (0.35) | ALDH1A1 | |
| SCHEMBL1077953 | 0.73 | RIPK1 (0.48) | RIPK1ALDH1A1TSHRTDP1 | |
| SCHEMBL18301597 | 0.73 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL4187976 | 0.72 | GAA (0.40) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239968-A1 | Process for preparing graft polyols using enol ethers as reaction moderators | BASF CORPORATION | 2005-10-27 | — | — | US | disclosed |
| EP-1589051-A1 | Process for preparing graft polyols using enol ethers as reaction moderators | BASF Corporation (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1192198-A1 | PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR | BASF CORPORATION (US) | 2002-04-03 | — | — | EP | disclosed |
| US-6172164-B1 | POLYMERIZING AN ETHYLENICALLY UNSATURATED MONOMER WITH A MACROMER WITH UNSATURATION IN PRESENCE OF FREE RADICAL INITIATOR BLEND OF TERT-AMYL PEROXY (2-ETHYLHEXANOATE AND 1,1'BIS(TERT-AMYL PEROXY) CYCLOHEXANE | BASF CORPORATION | 2001-01-09 | — | — | US | disclosed |
| WO-2000059971-A1 | PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR | BASF CORPORATION (DE) | 2000-10-12 | — | — | WO | disclosed |