Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 2/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18838245 | 0.77 | CYP17A1 (0.42) | HSD17B10MAPK1CYP17A1CYP1A2CYP3A4 | |
| SCHEMBL11199576 | 0.73 | NUDT1 (0.55) | HSD17B10MAOBMAOAHTTCYP3A4 | |
| SCHEMBL6328488 | 0.73 | HTT (0.41) | CYP2B6HSD17B10POLBMAPK1MAOB | |
| SCHEMBL6332152 | 0.73 | MAOB (0.39) | CYP2B6HSD17B10POLBMAPK1MAOB | |
| SCHEMBL30361260 | 0.72 | CYP1A2 (0.37) | HSD17B10CYP17A1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL29728856 | 0.72 | CYP17A1 (0.35) | HSD17B10CYP17A1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL26453885 | 0.72 | CYP1A2 (0.37) | HSD17B10CYP17A1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL15303366 | 0.66 | APP (0.43) | — | |
| SCHEMBL8177190 | 0.66 | PADI4 (0.36) | HSD17B10POLBMAPK1MAOBMAOA | |
| SCHEMBL11192994 | 0.65 | SMN1; SMN2 (0.39) | HSD17B10POLBMAPK1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050202973-A1 | Aryl-alkyne compounds as herbicides | SYNGENTA CROP PROTECTION, INC. | 2005-09-15 | — | — | US | disclosed |
| EP-1507768-A1 | ARYL-ALKYNE COMPOUNDS AS HERBICIDES | Syngenta Participations AG (CH) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003087067-A1 | ARYL-ALKYNE COMPOUNDS AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050202973-A1 | Aryl-alkyne compounds as herbicides | ALK, AGT, AHR | CYP2B6 95/4885HSD17B10 422/4885POLB 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.