Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328998 | 0.83 | POLB (0.38) | MAOBEGFRMAOAPOLBMAPK1 | |
| SCHEMBL6328488 | 0.81 | HTT (0.41) | MAOBEGFRMAOAHTTCYP2B6 | |
| SCHEMBL15472079 | 0.80 | PIK3CA (0.41) | KDRTRPA1 | |
| SCHEMBL21823514 | 0.77 | FPR2 (0.38) | MAOBMAOAPDE4B | |
| SCHEMBL9273767 | 0.73 | PDE4B (0.47) | MAOBEGFRMAOACYP2B6KMT2A | |
| SCHEMBL6598860 | 0.73 | MEN1 (0.50) | MAOBEGFRMAOACYP2B6KMT2A | |
| SCHEMBL29679102 | 0.73 | MEN1 (0.50) | MAOBEGFRMAOACYP2B6KMT2A | |
| SCHEMBL6165930 | 0.73 | CYP2B6 (0.36) | MAOBEGFRMAOAHTTCYP2B6 | |
| SCHEMBL6330405 | 0.72 | CHRNB2 (0.43) | EGFRCYP2B6KMT2AMEN1POLB | |
| SCHEMBL6327423 | 0.70 | P2RX3 (0.38) | MAOBEGFRPOLBMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107437-A1 | comprising pyridylalkynes used as preemergence and postemergence herbicides | SYNGENTA CROP PROTECTION, INC. | 2005-05-19 | — | — | US | disclosed |
| EP-1453807-A2 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050087-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107437-A1 | comprising pyridylalkynes used as preemergence and postemergence herbicides | DDT, CHRM1, CYP4X1 | MAOB 1601/4885EGFR 752/4885MAOA 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.