Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332152 | 0.81 | MAOB (0.39) | HTTCYP2B6MAOBEGFRMAOA | |
| SCHEMBL6327423 | 0.80 | P2RX3 (0.38) | MAOBEGFRTSHRLMNACYP2C9 | |
| SCHEMBL6830938 | 0.80 | TSHR (0.50) | HTTCYP2B6MAOBMAOATSHR | |
| SCHEMBL2432983 | 0.79 | SMN1; SMN2 (0.47) | HTTRXRAGRIN1GRIN2BTSHR | |
| SCHEMBL6830291 | 0.77 | MELK (0.40) | EGFRRXRAGRIN1GRIN2BTSHR | |
| SCHEMBL6329779 | 0.74 | CHRNB2 (0.45) | EGFRRXRAGRIN1GRIN2BTSHR | |
| SCHEMBL6339239 | 0.74 | GRM5 (0.39) | CYP2B6RXRAGRIN1GRIN2BTSHR | |
| SCHEMBL6165930 | 0.73 | CYP2B6 (0.36) | HTTCYP2B6MAOBEGFRMAOA | |
| SCHEMBL6815916 | 0.73 | HPGD (0.54) | HTTCYP2B6MAOBEGFRMAOA | |
| SCHEMBL23375370 | 0.73 | KDM4E (0.55) | TSHRLMNASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107437-A1 | comprising pyridylalkynes used as preemergence and postemergence herbicides | SYNGENTA CROP PROTECTION, INC. | 2005-05-19 | — | — | US | disclosed |
| EP-1453807-A2 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2004-09-08 | — | — | EP | disclosed |
| US-20040102325-A1 | Phenylpropynyloxypyridine herbicides | SYNGENTA CROP PROTECTION, INC. | 2004-05-27 | — | — | US | disclosed |
| WO-2003104206-A2 | HERBICIDALLY ACTIVE HETEROCYCLYLALKYNES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-12-18 | — | — | WO | disclosed |
| EP-1370140-A1 | PHENYLPROPYNYLOXYPYRIDINE HERBICIDES | Syngenta Participations AG (CH) | 2003-12-17 | — | — | EP | disclosed |
| WO-2003050087-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-06-19 | — | — | WO | disclosed |
| WO-2002028182-A1 | PHENYLPROPYNYLOXYPYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102325-A1 | Phenylpropynyloxypyridine herbicides | DDT, GSTM1, CYP4X1 | HTT 234/4885CYP2B6 473/4885MAOB 2181/4885 |
| US-20050107437-A1 | comprising pyridylalkynes used as preemergence and postemergence herbicides | DDT, CHRM1, CYP4X1 | HTT 1226/4885CYP2B6 31/4885MAOB 1601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.