Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665706 | 0.83 | PPARG (0.42) | CHEK2PDE2APDE10APPARGPPARD | |
| SCHEMBL13021436 | 0.72 | PPARG (0.43) | CHEK2PDE2APDE10APPARGPPARD | |
| SCHEMBL1664257 | 0.70 | PPARG (0.37) | CHEK2PDE2APPARGPPARD | |
| SCHEMBL5884528 | 0.70 | FFAR1 (0.39) | HCRTR1FFAR1HCRTR2CHRNB1CHRNB2 | |
| SCHEMBL13021438 | 0.67 | PPARG (0.39) | CHEK2PDE2APPARGPPARD | |
| SCHEMBL12796417 | 0.67 | PPARG (0.37) | CHEK2PDE2APPARGPPARD | |
| SCHEMBL16536568 | 0.66 | ALDH1A1 (0.45) | PDE2APDE10A | |
| SCHEMBL14499355 | 0.65 | PPARG (0.39) | CHEK2PDE2APPARGPPARD | |
| SCHEMBL12619638 | 0.63 | PPARG (0.37) | CHEK2PPARGPPARD | |
| SCHEMBL10327520 | 0.63 | NR1I2 (0.43) | PDE2APPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353911-A4 | ANTIVIRAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2005-01-05 | — | — | EP | disclosed |
| EP-1353911-A1 | ANTIVIRAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002050045-A1 | ANTIVIRAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2002-06-27 | — | — | WO | disclosed |