Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167634 | 1.00 | MGLL (0.46) | MGLLMAOBFFAR1FFAR4HDAC3 | |
| SCHEMBL6165379 | 0.97 | MGLL (0.41) | MGLLMAOBFFAR1FFAR4HDAC3 | |
| SCHEMBL6164962 | 0.95 | MAOB (0.43) | MGLLMAOBFFAR1FFAR4PGR | |
| SCHEMBL6164514 | 0.87 | MGLL (0.48) | MGLLMAOBFFAR1FFAR4HDAC3 | |
| SCHEMBL6166379 | 0.87 | MGLL (0.48) | MGLLMAOBFFAR1FFAR4HDAC3 | |
| SCHEMBL6622607 | 0.84 | HCAR2 (0.47) | MGLLMAOBFFAR1FFAR4HDAC3 | |
| SCHEMBL6165315 | 0.84 | MGLL (0.43) | MGLLMAOBFFAR1FFAR4HDAC3 | |
| SCHEMBL5775682 | 0.83 | MGLL (0.41) | MGLLMAOBFFAR1FFAR4HDAC3 | |
| SCHEMBL6166749 | 0.83 | MGLL (0.43) | MGLLMAOBFFAR1FFAR4HDAC3 | |
| SCHEMBL6164397 | 0.82 | PTPN1 (0.50) | MGLLMAOBFFAR1FFAR4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379516-B1 | ALKOXYCARBONYLAMINO BENZOIC ACID OR ALKOXYCARBONYLAMINO TETRAZOLYL PHENYL DERIVATIVES AS IP ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-11-16 | — | — | EP | claimed |