Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166144 | 0.95 | MGLL (0.46) | MAOBMGLLFFAR1FFAR4ENPP2 | |
| SCHEMBL6167634 | 0.95 | MGLL (0.46) | MAOBMGLLFFAR1FFAR4ENPP2 | |
| SCHEMBL6165379 | 0.92 | MGLL (0.41) | MAOBMGLLFFAR1FFAR4PGR | |
| SCHEMBL6164397 | 0.86 | PTPN1 (0.50) | MAOBMGLLFFAR1FFAR4ENPP2 | |
| SCHEMBL6163345 | 0.84 | CA12 (0.46) | MAOBMGLLFFAR1FFAR4ENPP2 | |
| SCHEMBL6162827 | 0.83 | MAOB (0.43) | MAOBMGLLFFAR1FFAR4ENPP2 | |
| SCHEMBL6166638 | 0.83 | ACLY (0.44) | MAOBMGLLFFAR1FFAR4ENPP2 | |
| SCHEMBL6163347 | 0.82 | TRPM2 (0.48) | MAOBMGLLFFAR1FFAR4PTPN1 | |
| SCHEMBL6163728 | 0.82 | CTSC (0.42) | MAOBMGLLFFAR1FFAR4ENPP2 | |
| SCHEMBL5776630 | 0.82 | MAOB (0.40) | MAOBMGLLFFAR1FFAR4ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379516-B1 | ALKOXYCARBONYLAMINO BENZOIC ACID OR ALKOXYCARBONYLAMINO TETRAZOLYL PHENYL DERIVATIVES AS IP ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-11-16 | — | — | EP | claimed |