SCHEMBL616660

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL616959	0.97	TRIM24 (0.42)	ALDH1A1LMNAMEN1PKMKMT2A
	SCHEMBL616333	0.86	HTR6 (0.48)	ALDH1A1LMNAMEN1PKMKMT2A
	Hydrochloric Acid SCHEMBL617112	0.85	HTR6 (0.47)	ALDH1A1LMNAMEN1PKMKMT2A
	SCHEMBL614832	0.84	HTR6 (0.51)	ALDH1A1LMNAMEN1PKMKMT2A
	Hydrochloric Acid SCHEMBL617391	0.83	HTR6 (0.50)	ALDH1A1LMNAMEN1PKMKMT2A
	SCHEMBL114169	0.83	TGFBR1 (0.49)	ALDH1A1LMNAMEN1PKMKMT2A
	SCHEMBL617383	0.82	HTR6 (0.52)	ALDH1A1LMNAPOLBSMN1; SMN2
	SCHEMBL618074	0.81	HTR6 (0.55)	—
	Hydrochloric Acid SCHEMBL617227	0.81	HTR6 (0.51)	ALDH1A1LMNAPOLBSMN1; SMN2
	Hydrochloric Acid SCHEMBL616021	0.81	HTR6 (0.54)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.