Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA7 | P43166 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AGER | Q15109 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770512 | 0.92 | BACE1 (0.65) | CA1CA2CA7CA9BACE1 | |
| SCHEMBL397022 | 0.82 | CA1 (0.78) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL2951470 | 0.79 | CYP2D6 (0.53) | BACE1MAPK1TSHRPOLBCYP2D6 | |
| SCHEMBL7153591 | 0.78 | CA1 (0.76) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL916141 | 0.78 | MAOA (0.56) | CA1CA2CA7CA9BACE1 | |
| SCHEMBL23540471 | 0.78 | CA1 (0.59) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL14865812 | 0.78 | MAOA (0.46) | CA1CA2CA7CA9BACE1 | |
| SCHEMBL29215324 | 0.78 | CA1 (0.59) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL23557188 | 0.78 | CA1 (0.59) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL2952028 | 0.77 | MAPT (0.50) | CA1CA2CA7CA9BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579819-B1 | NOVEL PYRIDONE DERIVATIVE HAVING AN AFFINITY FOR THE ANGIOTENSINE II RECEPTOR | AVENTIS PHARMA SA (FR) | 2005-12-21 | — | — | EP | disclosed |
| US-5674883-A | ANGIOTENSIN II INHIBITOR | ROUSSEL UCLAF (FR) | 1997-10-07 | — | — | US | disclosed |
| EP-0579819-A1 | NOVEL PYRIDONE DERIVATIVES, PREPARATION METHOD THEREFOR, NOVEL INTERMEDIATES THEREBY OBTAINED, THEIR USE AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1994-01-26 | — | — | EP | disclosed |
| WO-1993016049-A1 | NOVEL PYRIDONE DERIVATIVES, PREPARATION METHOD THEREFOR, NOVEL INTERMEDIATES THEREBY OBTAINED, THEIR USE AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL-UCLAF (FR) | 1993-08-19 | — | — | WO | disclosed |