SCHEMBL916141

SCHEMBL916141

OC(CSc1ccccc1)CSc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 1/20 0.52
CA1 P00915 4/20 0.49
CA2 P00918 4/20 0.49
CA4 P22748 4/20 0.49
CA7 P43166 4/20 0.49
CA9 Q16790 4/20 0.49
MTNR1A P48039 3/20 0.48
MTNR1B P49286 3/20 0.48
FFAR1 O14842 1/20 0.48
BACE1 P56817 5/20 0.45
MAPT P10636 1/20 0.44
PTGER1 P34995 1/20 0.42
PTGFR P43088 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14565232 0.91 MAOA (0.53) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL24098294 0.91 MAOA (0.48) MAOAMAOBALDH1A1MAPK1CA1
Alcohol SCHEMBL914156 0.91 MAOA (0.53) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL24098252 0.89 ALDH1A1 (0.48) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL1496771 0.89 MAOA (0.50) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL6482093 0.89 MAOA (0.50) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL6543393 0.89 MAOA (0.50) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL23391647 0.88 CA1 (0.52) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL1496561 0.87 MAOA (0.48) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL1496667 0.87 MAOA (0.53) MAOAMAOBALDH1A1MAPK1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12071515-B2 High dynamic range two-stage photopolymers THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2024-08-27 US disclosed
US-11780819-B2 Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings META PLATFORMS TECHNOLOGIES, LLC (US) 2023-10-10 US disclosed
US-11780819-B2 Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings META PLATFORMS TECHNOLOGIES, LLC (US) 2023-10-10 US disclosed
US-11780819-B2 Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings META PLATFORMS TECHNOLOGIES, LLC (US) 2023-10-10 US disclosed
EP-4244203-A1 SUBSTITUTED PROPANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC (US) 2023-09-20 EP disclosed
EP-4244204-A1 SUBSTITUTED MONO- AND POLY-PHENYL-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC (US) 2023-09-20 EP disclosed
CN-116568669-A Substituted mono-and poly-benzene nuclear monomers and polymers thereof for volume Bragg gratings 元平台技术有限公司 2023-08-08 CN disclosed
CN-116457336-A Substituted propane nuclear monomer for volume Bragg grating and polymer thereof 元平台技术有限公司 2023-07-18 CN disclosed
US-20230221637-A1 Holographic Recording Materials and Methods of Making Same UNIV COLORADO REGENTS (US) 2023-07-13 US disclosed
US-20230221637-A1 Holographic Recording Materials and Methods of Making Same UNIV COLORADO REGENTS (US) 2023-07-13 US disclosed
EP-1512704-A1 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2005-03-09 EP disclosed
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY 2005-03-03 US disclosed
EP-0839798-A2 Intermediates for preparating non-peptide retroviral protease inhibitors ABBOTT LABORATORIES (US) 1998-05-06 EP disclosed
EP-0511713-B1 Catalyst compositions SHELL INT RESEARCH (NL) 1997-10-01 EP disclosed
US-5670675-A Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1997-09-23 US disclosed
US-5545750-A TREATING HUMAN IMMUNODEFICIENCY VIRUS ABBOTT LABORATORIES (US) 1996-08-13 US disclosed
EP-0404228-B1 Catalyst compositions for the preparation of polymers of carbon monoxide with olefinically unsaturated compounds SHELL INT RESEARCH (NL) 1994-11-17 EP disclosed
EP-0511713-A1 Catalyst compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-11-04 EP disclosed
US-5142056-A Human immunodeficiency virus protease inhibitor ABBOTT LABORATORIES (US) 1992-08-25 US disclosed
EP-0402646-A1 Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1990-12-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom MACF1, WASF2, THEM6 MAOA 3034/4885MAOB 4170/4885ALDH1A1 1014/4885
US-11780819-B2 Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings SMAD2, ALK, SMAD3 MAOA 357/4885MAOB 959/4885ALDH1A1 611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.