Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 8/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6166845 | 0.80 | NOS3 (0.35) | F2TMPRSS6 | |
| SCHEMBL17992751 | 0.79 | EPHX1 (0.49) | — | |
| Trifluoroacetic Acid SCHEMBL6161743 | 0.79 | F2 (0.50) | F2TMPRSS6PRSS1F10 | |
| Trifluoroacetic Acid SCHEMBL6162719 | 0.78 | F9 (0.48) | F2PRSS1PRSS2PRSS3F10 | |
| Trifluoroacetic Acid SCHEMBL6165429 | 0.75 | F2 (0.55) | F2TMPRSS6F10 | |
| Trifluoroacetic Acid SCHEMBL6164542 | 0.74 | F2 (0.50) | F2TMPRSS6F10 | |
| SCHEMBL288337 | 0.71 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL202409 | 0.71 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL31538733 | 0.71 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL202408 | 0.71 | SLC7A5 (0.65) | PRSS1PRSS2PRSS3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | claimed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | claimed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | claimed |