Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5631282 | 0.93 | TUBB1 (0.51) | MEN1KMT2ACCR5L3MBTL1TUBB1 | |
| SCHEMBL21347524 | 0.82 | TUBB1 (0.59) | ERN1TRIM24TYRTRIM33CCR5 | |
| SCHEMBL31166742 | 0.81 | TRIM24 (0.52) | ERN1TRIM24TYRTRIM33MAOB | |
| SCHEMBL6168319 | 0.81 | CCR5 (0.42) | MAOBMEN1KMT2ACCR5TUBB1 | |
| SCHEMBL7147744 | 0.81 | TUBB1 (0.66) | MAOBMEN1KMT2ACCR5L3MBTL1 | |
| SCHEMBL28867061 | 0.79 | TRIM24 (0.73) | ERN1TRIM24TYRTRIM33MAOB | |
| SCHEMBL21822700 | 0.79 | ALDH1A1 (0.57) | ERN1TRIM24TYRTRIM33MEN1 | |
| SCHEMBL5286017 | 0.78 | ALDH1A1 (0.56) | TRIM24TYRTRIM33MAOBMEN1 | |
| SCHEMBL7150750 | 0.78 | TUBB1 (0.55) | MAOBMEN1KMT2ACCR5L3MBTL1 | |
| SCHEMBL23042981 | 0.78 | TUBB1 (0.49) | TRIM24TYRTRIM33CCR5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509499-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101959-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2003-12-11 | — | — | WO | disclosed |