Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 13/20 | 0.49 |
| ▸ | NPC1 | O15118 | 12/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053810 | 0.79 | PTGS1 (0.47) | PTGS1PTGS2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL21062849 | 0.77 | HPGD (0.41) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9517962 | 0.76 | NPC1 (0.48) | PTGS1PTGS2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8185284 | 0.75 | NPC1 (0.50) | PTGS1PTGS2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8189521 | 0.75 | PTGS1 (0.44) | PTGS1PTGS2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31731985 | 0.71 | RAB9A (0.67) | PTGS1PTGS2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2079932 | 0.70 | PTGS1 (0.58) | PTGS1PTGS2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3313092 | 0.70 | RAB9A (0.65) | PTGS1PTGS2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31154574 | 0.69 | RAB9A (0.74) | PTGS1PTGS2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29080554 | 0.69 | RAB9A (0.74) | PTGS1PTGS2RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949249-B1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-07-13 | — | — | EP | disclosed |