Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.65 |
| ▸ | NPC1 | O15118 | 13/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31731985 | 0.84 | RAB9A (0.67) | RAB9ANPC1KDM4EPOLBPTGS1 | |
| SCHEMBL2595462 | 0.79 | RAB9A (1.00) | RAB9ANPC1KDM4EPOLBPTGS1 | |
| SCHEMBL30558267 | 0.79 | RAB9A (0.61) | RAB9ANPC1KDM4EPOLBPTGS1 | |
| SCHEMBL13325909 | 0.78 | RAB9A (0.83) | RAB9ANPC1KDM4EPOLBPTGS1 | |
| Hydrochloric Acid SCHEMBL8874245 | 0.78 | RAB9A (0.97) | RAB9ANPC1KDM4EPOLBPTGS1 | |
| SCHEMBL2079932 | 0.77 | PTGS1 (0.58) | RAB9ANPC1KDM4EPOLBPTGS1 | |
| SCHEMBL31154574 | 0.77 | RAB9A (0.74) | RAB9ANPC1KDM4EPOLBPTGS1 | |
| SCHEMBL13325938 | 0.77 | RAB9A (0.80) | RAB9ANPC1KDM4EPOLBPTGS1 | |
| SCHEMBL29080554 | 0.77 | RAB9A (0.74) | RAB9ANPC1KDM4EPOLBPTGS1 | |
| SCHEMBL966793 | 0.77 | RAB9A (0.74) | RAB9ANPC1KDM4EPOLBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380565-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-12-28 | — | — | US | disclosed |
| WO-2023015199-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| EP-2919783-A1 | CYCLOPROPYL IMIDAZOPYRIDINE PDE10 INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014078217-A1 | CYCLOPROPYL IMIDAZOPYRIDINE PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-05-22 | — | — | WO | disclosed |
| US-20100105655-A1 | NOVEL COMPOUNDS 515 | ASTRAZENECA AB | 2010-04-29 | — | — | US | disclosed |
| EP-2032571-A1 | 3 -AMINO-IMIDAZO[1, 2-A]PYRIDINE DERIVATIVES AS SGLT INHIBITORS | Merck Patent GmbH (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007147478-A1 | 3 -AMINO-IMIDAZO[1, 2-A]PYRIDINE DERIVATIVES AS SGLT INHIBITORS | MERCK PATENT GMBH (DE) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416205-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NLRP3, NLRP1, NOD1 | RAB9A 1629/4885NPC1 545/4885KDM4E 3822/4885 |
| US-20100105655-A1 | NOVEL COMPOUNDS 515 | TYMS, ABCG2, UMPS | RAB9A 943/4885NPC1 279/4885KDM4E 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.