Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104688 | 0.91 | F10 (0.54) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL12700425 | 0.86 | CA1 (0.56) | CA12CA1CA2CA9 | |
| SCHEMBL6165511 | 0.84 | F10 (0.46) | F10PRSS1PRSS2PRSS3CHRNB2 | |
| SCHEMBL16088831 | 0.84 | CHRNB2 (0.71) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL16127992 | 0.81 | CHRNB2 (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12131737 | 0.81 | F10 (0.61) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL10143290 | 0.79 | F10 (0.59) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6793819 | 0.79 | RXFP1 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6167425 | 0.78 | F10 (0.43) | F10PRSS1PRSS2PRSS3CA12 | |
| SCHEMBL12700257 | 0.77 | BCAT2 (0.52) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |