Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6084684 | 0.91 | FKBP1A (0.48) | FKBP1AL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6087699 | 0.91 | FKBP1A (0.48) | FKBP1AL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6087133 | 0.91 | FKBP1A (0.48) | FKBP1AL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6087129 | 0.83 | CA2 (0.42) | CA2POLBHTR1AADRA2AADRA2B | |
| SCHEMBL6087694 | 0.83 | CA2 (0.42) | CA2POLBHTR1AADRA2AADRA2B | |
| SCHEMBL6084673 | 0.83 | CA2 (0.42) | CA2POLBHTR1AADRA2AADRA2B | |
| SCHEMBL6583228 | 0.81 | CCR4 (0.48) | CA2FKBP1AHTR1AADRA2AADRA2B | |
| SCHEMBL6583408 | 0.81 | CCR4 (0.48) | CA2FKBP1AHTR1AADRA2AADRA2B | |
| SCHEMBL6583410 | 0.80 | HTT (0.41) | CA2POLBHTR1ASIGMAR1 | |
| SCHEMBL6583233 | 0.80 | HTT (0.41) | CA2POLBHTR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383763-B1 | METHOD FOR PRODUCING 2-(-5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL)-CHROMANE | MERCK PATENT GMBH (DE) | 2005-10-12 | — | — | EP | disclosed |
| EP-1383763-A2 | METHOD FOR PRODUCING 2- -5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL]-CHROMANE | MERCK PATENT GmbH (DE) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002088117-A2 | METHOD FOR PRODUCING 2-[-5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL]-CHROMANE | MERCK PATENT GMBH (DE) | 2002-11-07 | — | — | WO | disclosed |