Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 11/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583408 | 1.00 | CCR4 (0.48) | CCR4FKBP1AHTR1ASIGMAR1ADRA2A | |
| SCHEMBL6087129 | 0.83 | CA2 (0.42) | HTR1ASIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL6084673 | 0.83 | CA2 (0.42) | HTR1ASIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL6087694 | 0.83 | CA2 (0.42) | HTR1ASIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL6087133 | 0.82 | FKBP1A (0.48) | FKBP1A | |
| SCHEMBL6087699 | 0.82 | FKBP1A (0.48) | FKBP1A | |
| SCHEMBL6084684 | 0.82 | FKBP1A (0.48) | FKBP1A | |
| SCHEMBL6167541 | 0.81 | CA2 (0.40) | FKBP1AHTR1ASIGMAR1ADRA2AADRA2B | |
| SCHEMBL4797076 | 0.80 | FKBP1A (0.65) | CCR4FKBP1AMMP1MMP7MMP8 | |
| SCHEMBL6583410 | 0.80 | HTT (0.41) | HTR1ASIGMAR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383763-A2 | METHOD FOR PRODUCING 2- -5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL]-CHROMANE | MERCK PATENT GmbH (DE) | 2004-01-28 | — | — | EP | claimed |
| WO-2002088117-A2 | METHOD FOR PRODUCING 2-[-5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL]-CHROMANE | MERCK PATENT GMBH (DE) | 2002-11-07 | — | — | WO | claimed |
| EP-1383763-A2 | METHOD FOR PRODUCING 2- -5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL]-CHROMANE | MERCK PATENT GmbH (DE) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002088117-A2 | METHOD FOR PRODUCING 2-[-5-(4-FLUOROPHENYL)-3-PYRIDYLMETHYLAMINOMETHYL]-CHROMANE | MERCK PATENT GMBH (DE) | 2002-11-07 | — | — | WO | disclosed |