Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 2/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620717 | 0.83 | HPGD (0.43) | HPGDACKR3GAARAB9ANPC1 | |
| SCHEMBL10423017 | 0.78 | ALDH1A1 (0.40) | HPGDGAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6221426 | 0.74 | KEAP1 (0.49) | KEAP1NFE2L2HPGDRAB9ANPC1 | |
| SCHEMBL19971415 | 0.74 | KEAP1 (0.49) | KEAP1NFE2L2HPGDRAB9ANPC1 | |
| SCHEMBL141512 | 0.72 | CNR1 (0.35) | CNR1CNR2PDE4B | |
| SCHEMBL5779089 | 0.71 | KEAP1 (0.49) | KEAP1NFE2L2HPGDACKR3GAA | |
| SCHEMBL5779087 | 0.71 | KEAP1 (0.49) | KEAP1NFE2L2HPGDACKR3GAA | |
| SCHEMBL4513190 | 0.70 | HPGD (0.51) | KEAP1NFE2L2HPGDACKR3GAA | |
| SCHEMBL23497859 | 0.69 | KEAP1 (0.46) | KEAP1NFE2L2HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL5256943 | 0.69 | KEAP1 (0.40) | KEAP1NFE2L2HPGDACKR3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341781-B1 | ANTIMICROBIAL QUINOLONES | PROCTER & GAMBLE (US) | 2005-09-14 | — | — | EP | disclosed |
| US-6900224-B2 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2004-02-26 | — | — | US | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |
| US-20040029882-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE CO. | 2004-02-12 | — | — | US | disclosed |
| US-6645981-B2 | For therapy of microbial infection | THE PROCTER & GAMBLE COMPANY | 2003-11-11 | — | — | US | disclosed |
| US-20030008894-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, NQO2, Q6ZSR9 | KEAP1 1044/4885NFE2L2 1732/4885HPGD 1055/4885 |
| US-20030008894-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, NQO2, Q6ZSR9 | KEAP1 1044/4885NFE2L2 1732/4885HPGD 1055/4885 |
| US-20040029882-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, NQO2, Q6ZSR9 | KEAP1 1044/4885NFE2L2 1732/4885HPGD 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.