Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.32 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820423 | 0.86 | NR3C1 (0.38) | NR3C1NR3C2PGR | |
| SCHEMBL4826616 | 0.79 | ALDH1A1 (0.41) | NR3C1NR3C2PGR | |
| SCHEMBL4822589 | 0.77 | AOC3 (0.33) | — | |
| SCHEMBL4820111 | 0.75 | NR3C1 (0.35) | NR3C1NR3C2PGR | |
| SCHEMBL4822532 | 0.70 | NR3C1 (0.61) | NR3C1NR3C2PGR | |
| SCHEMBL5202432 | 0.69 | NR3C1 (0.34) | NR3C1NR3C2PGR | |
| SCHEMBL3533407 | 0.66 | NR3C1 (0.43) | NR3C1NR3C2PGR | |
| SCHEMBL3682425 | 0.63 | NR3C1 (0.38) | NR3C1NR3C2PGR | |
| SCHEMBL3531222 | 0.62 | NR3C1 (0.38) | NR3C1NR3C2PGR | |
| SCHEMBL14081376 | 0.62 | NR3C1 (0.59) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1659144-A | Quinoline and isoquinoline derivatives, process for their preparation and their use as inflammation inhibitors | SCHERING AG (DE) | 2005-08-24 | — | — | CN | disclosed |
| EP-1492771-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082827-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-09 | — | — | WO | disclosed |