Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780365 | 0.80 | PKM (0.53) | PKMALDH1A1MAPTTDP1CYP1A2 | |
| SCHEMBL27540293 | 0.80 | PKM (0.49) | PKMALDH1A1MAPTTDP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7112027 | 0.79 | PKM (0.51) | PKMALDH1A1MAPTTDP1CYP1A2 | |
| SCHEMBL6168627 | 0.79 | PKM (0.40) | PKMALDH1A1MAPTTDP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7125063 | 0.78 | PKM (0.39) | PKMALDH1A1MAPTTDP1CYP1A2 | |
| SCHEMBL6168164 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTMAOALMNA | |
| SCHEMBL7111868 | 0.74 | MAPT (0.49) | PKMALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6935206 | 0.72 | PKM (0.50) | PKMALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL6167007 | 0.72 | MAPT (0.37) | PKMALDH1A1MAPTTDP1CYP1A2 | |
| SCHEMBL3373070 | 0.71 | PKM (0.61) | PKMALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147090-B1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR DYEING KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2005-11-23 | — | — | EP | disclosed |
| US-6660046-B1 | Cationic oxidation bases, their use of dyeing keratin fibres, dyeing compositions and dyeing methods | L'OREAL S.A. (FR) | 2003-12-09 | — | — | US | disclosed |
| EP-1147090-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR DYEING KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000043367-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR DYEING KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 2000-07-27 | — | — | WO | disclosed |