Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 19/20 | 0.66 |
| ▸ | CTSS | P25774 | 18/20 | 0.66 |
| ▸ | CTSK | P43235 | 17/20 | 0.66 |
| ▸ | CTSB | P07858 | 16/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5514058 | 1.00 | CTSL (0.66) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6170188 | 0.85 | CTSK (0.67) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5523854 | 0.85 | CTSK (0.67) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5514769 | 0.84 | CTSK (0.63) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5518382 | 0.84 | CTSK (0.57) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5512632 | 0.81 | CTSL (0.70) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2156992 | 0.80 | CTSL (1.00) | CTSLCTSSCTSKCTSB | |
| SCHEMBL2156187 | 0.80 | CTSL (1.00) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6182313 | 0.79 | CTSS (0.53) | CTSLCTSSCTSKCTSB | |
| SCHEMBL5516546 | 0.79 | CTSS (0.53) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537074-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA INC. (CA) | 2005-06-08 | — | — | EP | claimed |
| WO-2004022526-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2004-03-18 | — | — | WO | claimed |