SCHEMBL6168912

SCHEMBL6168912

CNc1ccc(N(C=O)c2nccs2)o1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 1/20 0.34
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6206130 0.82 ADORA2A (0.33) FFAR2
SCHEMBL6167615 0.80 ALDH1A1 (0.32) FFAR2ALDH1A1
SCHEMBL6167560 0.76 FFAR2 (0.32) FFAR2
SCHEMBL6170282 0.76 MAPT (0.34) NPC1ALDH1A1LMNAMAPTHPGD
SCHEMBL6168118 0.74 POLB (0.41) NPC1ALDH1A1LMNAMAPTRAB9A
SCHEMBL6167527 0.70
SCHEMBL6169943 0.70
SCHEMBL9280655 0.68 PDPK1 (0.39) FFAR2NPC1ALDH1A1LMNAHPGD
SCHEMBL6590409 0.65
SCHEMBL6211527 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1498109-A1 Furan derivatives and dyeing composition comprising a furan derivative as coupler L'OREAL (FR) 2005-01-19 EP claimed
EP-1498109-A1 Furan derivatives and dyeing composition comprising a furan derivative as coupler L'OREAL (FR) 2005-01-19 EP disclosed