Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251789 | 0.80 | FBP1 (0.42) | LMNARAB9AKMT2AMEN1FFAR2 | |
| SCHEMBL6228985 | 0.76 | KCNA5 (0.36) | NPC1RAB9APIM1 | |
| SCHEMBL9305341 | 0.76 | PDPK1 (0.45) | PDPK1LMNAFFAR1FFAR4TRPM8 | |
| SCHEMBL28308906 | 0.74 | TRPM8 (0.33) | TRPM8HDAC1FFAR2 | |
| SCHEMBL2988998 | 0.74 | NPC1 (0.50) | PDPK1LMNAFFAR1FFAR4NR3C1 | |
| SCHEMBL6251427 | 0.74 | ALDH1A1 (0.43) | TRPM8KDM4ETSHRALDH1A1GAA | |
| SCHEMBL4239450 | 0.73 | PDPK1 (0.42) | PDPK1LMNAFFAR1FFAR4NR3C1 | |
| SCHEMBL1896858 | 0.72 | LMNA (0.53) | PDPK1LMNAFFAR1FFAR4NR3C1 | |
| SCHEMBL10599572 | 0.72 | KDM4E (0.40) | PDPK1LMNAFFAR1FFAR4TRPM8 | |
| SCHEMBL43388 | 0.72 | ALDH1A1 (0.42) | LMNATRPM8NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371950-B1 | Substituted thiazoles and their use as fungicides | MONSANTO CO (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5045554-A | Fluoro compounds, rice sheath blight, Basidiomycetes type fungus | MONSANTO COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| WO-1991001311-A1 | SUBSTITUTED CARBOXANILIDOTHIAZOLES AND THEIR USE AS FUNGICIDES | MONSANTO COMPANY (US) | 1991-02-07 | — | — | WO | disclosed |
| EP-0371950-A2 | Substituted thiazoles and their use as fungicides | Monsanto Company (US) | 1990-06-06 | — | — | EP | disclosed |