Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PNLIP | P16233 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 4/20 | 0.47 |
| ▸ | FNTB | P49356 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169592 | 1.00 | CA2 (0.56) | CA2MMP2MMP9MMP8MMP14 | |
| SCHEMBL2282234 | 0.90 | MEN1 (0.57) | CA2CA9CA14LMNAMEN1 | |
| SCHEMBL669319 | 0.90 | MEN1 (0.57) | CA2CA9CA14LMNAMEN1 | |
| SCHEMBL1421530 | 0.90 | MEN1 (0.57) | CA2CA9CA14LMNAMEN1 | |
| SCHEMBL5955145 | 0.87 | MMP2 (0.57) | MMP2MMP8MMP14CA9CA14 | |
| SCHEMBL5955152 | 0.87 | MMP2 (0.57) | MMP2MMP8MMP14CA9CA14 | |
| Oxalic Acid SCHEMBL16649321 | 0.86 | MEN1 (0.54) | CA2CA9CA14LMNAMEN1 | |
| SCHEMBL5954381 | 0.86 | FNTA (0.52) | NPY5RKMT2AL3MBTL1FNTAFNTB | |
| SCHEMBL5954378 | 0.86 | FNTA (0.52) | NPY5RKMT2AL3MBTL1FNTAFNTB | |
| SCHEMBL5954848 | 0.85 | MEN1 (0.47) | MMP2MMP8MMP14CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |