SCHEMBL669319

SCHEMBL669319

CC(Nc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
LMNA P02545 1/20 0.57
TSHR P16473 1/20 0.48
HTT P42858 3/20 0.46
MAPT P10636 2/20 0.46
MAPK1 P28482 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ALDH1A1 P00352 1/20 0.46
FFAR2 O15552 1/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.43
PKM P14618 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
NLRP1 Q9C000 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2282234 1.00 MEN1 (0.57) MEN1KMT2ALMNATSHRHTT
SCHEMBL1421530 1.00 MEN1 (0.57) MEN1KMT2ALMNATSHRHTT
Oxalic Acid SCHEMBL16649321 0.96 MEN1 (0.54) MEN1KMT2ALMNATSHRHTT
SCHEMBL6169592 0.90 CA2 (0.56) MEN1KMT2ALMNATSHRHTT
SCHEMBL6169593 0.90 CA2 (0.56) MEN1KMT2ALMNATSHRHTT
SCHEMBL8758435 0.84 KIF11 (0.49) MEN1KMT2AMAPTMAPK1ALDH1A1
SCHEMBL13890445 0.84 MEN1 (0.61) MEN1KMT2ALMNATSHRHTT
SCHEMBL133675 0.84 KIF11 (0.49) MEN1KMT2AMAPTMAPK1ALDH1A1
SCHEMBL7717526 0.84 KIF11 (0.49) MEN1KMT2AMAPTMAPK1ALDH1A1
SCHEMBL7089012 0.82 CA12 (0.47) MEN1KMT2ALMNATSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081907-A Radiolabeled bombesin derivative compounds for in vivo imaging of the Gastrin Releasing Peptide Receptor (GRPR) and treatment of GRPR-related disorders 省卫生服务机构 2025-06-03 CN claimed
CN-118812647-A Novel insect short neuropeptide sNPF analogue and application thereof 四川轻化工大学 2024-10-22 CN claimed
CN-118104562-A High-yield seed production method for peppers 遵义市农业科学研究院 2024-05-31 CN claimed
EP-3374520-A1 BIOSENSORS Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2018-09-19 EP claimed
WO-2017081684-A1 BIOSENSORS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2017-05-18 WO claimed
US-7538245-B2 Process for the manufacture of an enantiopure compound SOLVAY S.A. (BE) 2009-05-26 US claimed
US-20070027326-A1 Process for the manufacture of an enantiopure compound SOLVAY S.A. (BE) 2007-02-01 US claimed
US-7138538-B2 Process for the separation of enantiomers and enantiopure reagent SOLVAY (SOCIETE ANONYME) (BE) 2006-11-21 US claimed
EP-1664084-A1 PROCESS FOR THE MANUFACTURE OF AN ENANTIOPURE COMPOUND SOLVAY (Société Anonyme) (BE) 2006-06-07 EP claimed
WO-2005023838-A1 PROCESS FOR THE MANUFACTURE OF AN ENANTIOPURE COMPOUND Solvay (Société Anonyme) (BE) 2005-03-17 WO claimed
CN-1387567-A Conjugates between peptides and nucleic acid analogues such as PNA, LNA, or morpholino PANTHECO AS (DK) 2002-12-25 CN claimed
EP-1046627-A2 Enantiopure reagents and process for the separation of enantiomers SOLVAY (Société Anonyme) (BE) 2000-10-25 EP claimed
US-5952346-A INHIBITS THE ACTIONS OF THE ALZHEIMER'S PROTEIN AMYLOID (BETA/A4) IN ISOLATED ENDOTHELIAL CELLS; QUINOLINE DERIVATIVES HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) 1999-09-14 US claimed
WO-1998010786-A2 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF SYNDROME X OF REAVEN COHEN YAROM (IL) 1998-03-19 WO claimed
CN-1132756-A Antiviral ethers of aspartate protease substrate isosteres CIBA GEIGY AG (CH) 1996-10-09 CN claimed
WO-1996016980-A1 MORPHOLINOETHYLAMIDE DERIVATIVES NOVARTIS AG (CH) 1996-06-06 WO claimed
EP-0203031-B1 BIOLOGICALLY ACTIVE LYSINE CONTAINING OCTAPEPTIDES The Administrators of The Tulane University Educational Fund (US) 1992-07-29 EP claimed
WO-1992007845-A1 DERIVATIVES OF AMINO ACIDS AS INHIBITORS OF RENIN, METHODS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-14 WO claimed
EP-0483403-A1 Derivatives of amino acids as inhibitors of renin, methods for their preparation, medicaments containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-06 EP claimed
US-4855286-A HYPOTENSIVE AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027326-A1 Process for the manufacture of an enantiopure compound AMD1, DAO, DDC MEN1 3808/4885KMT2A 3516/4885LMNA 2074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.