Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.50 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CPA3 | P15088 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167389 | 0.88 | ECE1 (0.51) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7271417 | 0.83 | MME (0.65) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL6159992 | 0.82 | MME (0.69) | MMEACE | |
| SCHEMBL6162138 | 0.82 | MME (0.69) | MMEACE | |
| SCHEMBL6159984 | 0.82 | MME (0.69) | MMEACE | |
| SCHEMBL6169697 | 0.82 | ROCK2 (0.40) | — | |
| SCHEMBL5097467 | 0.82 | MME (0.57) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL6168382 | 0.81 | WNT3A (0.47) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9724811 | 0.80 | MME (0.65) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL6169634 | 0.80 | MME (0.52) | MMEACEALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877740-B1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2005-03-30 | — | — | EP | claimed |