Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 4/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003801 | 0.92 | ALDH1A1 (0.43) | LMNAALDH1A1SMN1; SMN2HPGDGALR2 | |
| SCHEMBL7010043 | 0.85 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2HPGDGALR2 | |
| SCHEMBL7007303 | 0.84 | ALDH1A1 (0.46) | LMNAALDH1A1SMN1; SMN2HPGDGALR2 | |
| Acrylic Acid SCHEMBL6169907 | 0.79 | L3MBTL1 (0.36) | LMNAALDH1A1SMN1; SMN2HPGDGALR2 | |
| SCHEMBL1301604 | 0.76 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2HPGDGALR2 | |
| SCHEMBL3190199 | 0.75 | MEN1 (0.41) | LMNAALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL7010910 | 0.74 | ALDH1A1 (0.46) | LMNAALDH1A1SMN1; SMN2HPGDGALR2 | |
| SCHEMBL5666711 | 0.74 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL10423012 | 0.73 | MAPT (0.47) | LMNAALDH1A1SMN1; SMN2HPGDGALR2 | |
| SCHEMBL9860199 | 0.73 | ALDH1A1 (0.44) | LMNAALDH1A1SMN1; SMN2HPGDGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |