SCHEMBL6169988

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6168129	0.94	MAP4K4 (0.54)	MAP4K4CLK2DYRK1ASRPK1CLK4
	SCHEMBL6170667	0.86	MAP4K4 (0.56)	MAP4K4CLK2DYRK1ASRPK1CLK4
	SCHEMBL6170774	0.86	NR1H4 (0.62)	MAP4K4CLK2DYRK1ASRPK1CLK4
	SCHEMBL6169846	0.85	ESR1 (0.55)	BTKF10NR1H4PPARGPPARA
	SCHEMBL6171764	0.83	RAB9A (0.53)	MAP4K4CLK2DYRK1ASRPK1CLK4
	SCHEMBL6169012	0.81	MAP4K4 (0.57)	MAP4K4CLK2DYRK1ASRPK1CLK4
	SCHEMBL7366501	0.80	F10 (0.47)	F10ALDH1A1NR1H4PPARGPPARA
	SCHEMBL5226932	0.80	NR1H4 (0.57)	F10NPC1RAB9ALMNAMAPT
	SCHEMBL7371060	0.79	F10 (0.46)	F10NR1H4PPARGPPARAHPGD
	SCHEMBL6169059	0.79	ESR1 (0.56)	BTKMEN1KMT2ANR1H4PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.