Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168721 | 0.77 | CNR1 (0.54) | MEN1TSHRKMT2AALDH1A1GAA | |
| SCHEMBL6169138 | 0.75 | CNR1 (0.49) | MEN1TSHRKMT2AHTTALDH1A1 | |
| SCHEMBL6169070 | 0.71 | FAAH (0.50) | TSHRALDH1A1GAAFAAHCNR1 | |
| SCHEMBL5954860 | 0.71 | CSF1R (0.43) | KMT2AHTTALDH1A1HRH3CSF1R | |
| SCHEMBL6167711 | 0.70 | CNR1 (0.50) | TSHRHTTALDH1A1GAACNR1 | |
| SCHEMBL6624966 | 0.70 | MAPT (0.47) | MEN1TSHRKMT2AHTTALDH1A1 | |
| SCHEMBL11720675 | 0.69 | HRH1 (0.77) | HRH3HRH1CNR1 | |
| SCHEMBL7567492 | 0.67 | HRH1 (0.61) | ALDH1A1HRH3HRH1CNR1 | |
| SCHEMBL6625012 | 0.67 | CNR1 (0.46) | MEN1TSHRKMT2AHTTALDH1A1 | |
| SCHEMBL6168870 | 0.67 | GAA (0.46) | MEN1KMT2AALDH1A1GAACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |