Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486579 | 0.88 | CNR1 (0.59) | CNR1ALDH1A1LMNAGAAHDAC6 | |
| SCHEMBL6169138 | 0.83 | CNR1 (0.49) | CNR1ALDH1A1LMNAGAAMMP2 | |
| SCHEMBL6167711 | 0.79 | CNR1 (0.50) | CNR1ALDH1A1LMNAGAAMMP2 | |
| SCHEMBL6170816 | 0.77 | MEN1 (0.47) | CNR1ALDH1A1GAATSHRMEN1 | |
| SCHEMBL6169070 | 0.75 | FAAH (0.50) | CNR1ALDH1A1LMNAGAAMMP2 | |
| SCHEMBL6168870 | 0.75 | GAA (0.46) | CNR1ALDH1A1LMNAGAAMMP2 | |
| SCHEMBL6169738 | 0.74 | CNR1 (0.43) | CNR1ALDH1A1LMNAGAAMMP2 | |
| SCHEMBL6835850 | 0.72 | MMP2 (0.50) | ALDH1A1LMNAGAAMMP2MMP9 | |
| SCHEMBL6168712 | 0.72 | CNR1 (0.46) | CNR1ALDH1A1GAAMMP2MMP9 | |
| SCHEMBL6168079 | 0.71 | LMNA (0.47) | CNR1ALDH1A1LMNAMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |