Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 12/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170967 | 0.75 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL5343889 | 0.62 | SLC6A4 (0.50) | NOS1NOS3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5340091 | 0.59 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6873406 | 0.59 | CRHR1 (0.54) | CRHR1MAPTTHRB | |
| SCHEMBL735118 | 0.59 | SLC6A4 (0.68) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5675723 | 0.58 | MEN1 (0.54) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9172783 | 0.58 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL194469 | 0.58 | NOS1 (1.00) | NOS1NOS3 | |
| SCHEMBL5829892 | 0.58 | IDO1 (0.47) | MAPT | |
| SCHEMBL27494431 | 0.57 | GAA (0.67) | NOS1NOS3MAPTSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555265-A1 | 7-PHENYL PYRAZOLOPYRIDINE COMPOUNDS | Eisai Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |