SCHEMBL5829892

SCHEMBL5829892

CCc1cccc(OC)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.47
TAAR1 Q96RJ0 1/20 0.47
ATP4A P20648 1/20 0.46
ATP4B P51164 1/20 0.46
ALDH1A1 P00352 2/20 0.45
ADRA2B P18089 1/20 0.45
PTGS1 P23219 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
ALOX5 P09917 1/20 0.43
PTGS2 P35354 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL22169120 0.91 IDO1 (0.44) IDO1TAAR1ATP4AATP4BALDH1A1
SCHEMBL6745155 0.85 GABRA1 (0.43) IDO1ALDH1A1MAPTL3MBTL1HPGD
SCHEMBL11139082 0.84 ALOX5 (0.49) IDO1TAAR1ATP4AATP4BALDH1A1
SCHEMBL1161154 0.83 TAAR1 (0.52) IDO1TAAR1ATP4AATP4BALDH1A1
SCHEMBL30122828 0.83 TAAR1 (0.52) IDO1TAAR1ATP4AATP4BALDH1A1
Hydrochloric Acid SCHEMBL7253568 0.82 ALOX5 (0.47) IDO1TAAR1ATP4AATP4BALDH1A1
SCHEMBL11139017 0.82 L3MBTL1 (0.56) ALDH1A1TDP1MAPTGAAL3MBTL1
SCHEMBL1353991 0.82 IDO1 (0.48) IDO1TAAR1ATP4AATP4BALDH1A1
SCHEMBL17058000 0.82 IDO1 (0.46) IDO1TAAR1ATP4AATP4BALDH1A1
SCHEMBL2921543 0.82 IDO1 (0.47) IDO1TAAR1ATP4AATP4BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9249091-B2 Post-treated sulfurized salt of an alkyl-substituted hydroxyaromatic composition CHEVRON ORONITE COMPANY LLC (US) 2016-02-02 US claimed
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2013-06-27 US claimed
US-7056986-B2 ethylene monomer can be a vinyl ketone, ether, ester, halide, nitrile, aromatic, or an allyl ether; acrylic monomer can be a mono- or diacid or monoester of a diacid; a monoamine, a guanidine compound, and an aromatic diamine; improved vulcanizability, balance between processability and compression set DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-06-06 US claimed
US-12109291-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-10-08 US disclosed
US-12102704-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations HENKEL AG & CO. KGAA (DE) 2024-10-01 US disclosed
US-20230270648-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations HENKEL AG & CO. KGAA (DE) 2023-08-31 US disclosed
CN-110249004-B Polyimide precursor composition 东京应化工业株式会社 2022-07-19 CN disclosed
CN-108774561-B Sulfurized salts of post-treated alkyl-substituted hydroxyaromatic compositions 雪佛龙奥伦耐有限责任公司 2022-07-01 CN disclosed
CN-108389512-B Laminate, flexible device, and method for producing laminate 东京应化工业株式会社 2022-04-15 CN disclosed
CN-108387954-B Laminate, flexible device, and method for producing laminate 东京应化工业株式会社 2022-01-18 CN disclosed
EP-3237385-B1 MUTANT IDH1 INHIBITORS USEFUL FOR TREATING CANCER US HEALTH (US) 2021-11-24 EP disclosed
US-4147804-A ANTIARRHYTHMIA AGENTS WILLIAM H. RORER, INC. (US) 1979-04-03 US disclosed
US-4060635-A Amidinoureas for treating diarrhea WILLIAM H. RORER, INC. (US) 1977-11-29 US disclosed
US-4046554-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-09-06 US disclosed
US-4012222-A Herbicidal compositions containing dioxolane substituted anilids and method therefor VELSICOL CHEMICAL CORPORATION (US) 1977-03-15 US disclosed
US-3966811-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-06-29 US disclosed
US-3948950-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-04-06 US disclosed
US-3946045-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-03-23 US disclosed
US-3942972-A Dioxolane substituted α-haloanilides as herbicides VELSICOL CHEMICAL CORPORATION (US) 1976-03-09 US disclosed
US-3940259-A Dioxane substituted-α-haloanilides as herbicides VELSICOL CHEMICAL CORPORATION (US) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12109291-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, ALDH2 IDO1 1884/4885TAAR1 1353/4885ATP4A 1773/4885
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION TST, PAH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 IDO1 640/4885TAAR1 374/4885ATP4A 3291/4885
US-20230270648-A1 Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations KRT18, ALDH5A1, ALDH2 IDO1 1280/4885TAAR1 996/4885ATP4A 1655/4885
US-12102704-B2 Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations KRT18, ALDH5A1, ALDH2 IDO1 1280/4885TAAR1 996/4885ATP4A 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.