Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 10/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171676 | 0.84 | EPHX2 (0.40) | HPGDTSHRACHEEPHX2EPHX1 | |
| SCHEMBL6170813 | 0.81 | ACHE (0.39) | ACHEEPHX2EPHX1ATM | |
| SCHEMBL2301673 | 0.76 | EPHX2 (0.50) | EPHX2EPHX1ATM | |
| SCHEMBL6571002 | 0.74 | EPHX2 (0.56) | HPGDEPHX2ATM | |
| SCHEMBL7770641 | 0.74 | TSHR (0.47) | HPGDTSHREPHX2ATMCNR1 | |
| SCHEMBL2946547 | 0.73 | EPHX1 (0.44) | HPGDTSHRACHEEPHX1ATM | |
| SCHEMBL14321822 | 0.73 | HPGD (0.50) | HPGDTSHRACHEEPHX1ATM | |
| SCHEMBL14321821 | 0.73 | HPGD (0.50) | HPGDTSHRACHEEPHX1ATM | |
| SCHEMBL1486852 | 0.73 | ACHE (0.55) | HPGDTSHRACHEEPHX1ATM | |
| SCHEMBL7774748 | 0.73 | TSHR (0.49) | HPGDTSHREPHX2ATMCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |