Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.56 |
| ▸ | TOP1 | P11387 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | FABP4 | P15090 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029105 | 0.94 | EPHX2 (0.64) | EPHX2TOP1PPARGPPARDPPARA | |
| SCHEMBL2301673 | 0.92 | EPHX2 (0.50) | EPHX2TOP1PPARGPPARDPPARA | |
| SCHEMBL7449007 | 0.80 | EPHX2 (0.49) | EPHX2MAPTBLMHSD17B10USP2 | |
| SCHEMBL2946547 | 0.78 | EPHX1 (0.44) | ALDH1A1HPGDATM | |
| SCHEMBL11021688 | 0.76 | ATM (0.61) | TOP1PPARGPPARDPPARAMAPT | |
| SCHEMBL7789634 | 0.76 | CTSK (0.55) | LMNARECQLKMT2ATDP1MEN1 | |
| SCHEMBL9956131 | 0.76 | HCAR2 (0.58) | MAPTALDH1A1HPGDNPSR1ATM | |
| SCHEMBL6570238 | 0.75 | BLM (0.43) | TOP1PPARGPPARDPPARAMAPT | |
| SCHEMBL6170813 | 0.74 | ACHE (0.39) | EPHX2ATM | |
| SCHEMBL6171676 | 0.74 | EPHX2 (0.40) | EPHX2ALDH1A1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455809-A2 | INHIBITORS OF HEPATITIS C VIRUS | Bristol-Myers Squibb Company (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053349-A2 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |