Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171271 | 0.84 | HPGD (0.41) | EPHX2ACHETSHRHPGDEPHX1 | |
| SCHEMBL6170813 | 0.81 | ACHE (0.39) | EPHX2ACHEEPHX1ATM | |
| SCHEMBL2301673 | 0.76 | EPHX2 (0.50) | EPHX2EPHX1ATM | |
| SCHEMBL1029105 | 0.75 | EPHX2 (0.64) | EPHX2ALDH1A1TSHRHPGDATM | |
| SCHEMBL6571002 | 0.74 | EPHX2 (0.56) | EPHX2ALDH1A1HPGDATM | |
| SCHEMBL2946547 | 0.73 | EPHX1 (0.44) | ACHEALDH1A1TSHRHPGDEPHX1 | |
| SCHEMBL28397108 | 0.71 | EPHX1 (0.48) | ACHEALDH1A1TSHRHPGDEPHX1 | |
| SCHEMBL7403483 | 0.71 | EPHX1 (0.48) | ACHEALDH1A1TSHRHPGDEPHX1 | |
| SCHEMBL7458595 | 0.70 | ATM (0.52) | ACHEALDH1A1TSHRHPGDEPHX1 | |
| SCHEMBL14321822 | 0.70 | HPGD (0.50) | ACHEALDH1A1TSHRHPGDEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |